Coronary artery disease

Rethinking saturated fats

A paper that will most likely raise a lot of controversies was published in JACC beginning of august 2020, one of the top scientific journals in cardiology. The article goes through a lot more then I cover here, but I wanted to make accessible one of the main reasons why saturated fats have been erroneously demonized (if LDL and cholesterol are all clear for you here’s my main point: Under the presumption that either LDLc or all LDLp were important contributors to atherosclerosis, a diet that showed an increase in either of these was (and still is by most) considered dangerous and to be avoided).

Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene

- **Background** Genome-wide association studies (GWAS) have identified hundreds of loci associated with coronary artery disease (CAD) and blood pressure (BP) or hypertension. Many of these loci are not linked to traditional risk factors, nor do they …